I use Wholly Genes' "The Master Genealogist" to manage my research data, photos and sources plus John Cardinal's "Second Site" to prepare CD-ROMs for relatives and to publish my TMG data on the Web
These programs are suitable for both professional researchers and learners (like me) as they are comprehensive, flexible and extremely well supported which is important.

For further information, click the links to the websites below.
 

Wholly Genes' The Master Genealogist
John Cardinal's Second Site
Various Second Site examples